spiro compounds การใช้

Assignment of absolute configuration of spiro compounds has been challenging, but a number of each type have been unequivocally assigned.
"' Fluorescamine "'is a spiro compound that is not fluorescent itself, but reacts with primary amines to form highly fluorescent products.
Spiro compounds are present throughout the natural world, some cases of which have been exploited to provide tool compounds for biomedical study and to serve as scaffolds for the design of therapeutic agents with novel shapes.
A further example of an acetal formed from a cyclic ketone, except with a dithiol, is the spiro compound spirapril, which has a five-membered ring formed from 1, 2-ethanedithiol.
The simplest spiro compounds are bicyclic ( having just two rings ), or have a bicyclic portion as part of the larger ring system, in either case with the two rings connected through the defining single common atom.